abstract：:BACKGROUND This study investigated the influence of surgical timing on the treatment of terrible triad of the elbow (TTE). MATERIAL AND METHODS After exclusion, 63 patients were enrolled in this study: 20 patients were classified into the emergency group (group A, within 24 h after injury), 26 into the early surgery g...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zhou C,Lin J,Xu J,Lin R,Chen K,Sun S,Kong J,Shui X

更新日期：2018-07-09 00:00:00

abstract：:BACKGROUND The aim of this study was to evaluate the elution of BisGMA, UDMA, TEGDMA, and HEMA monomers from flowable bulk fill composite resins with different resin matrix compositions, polymerized in 4-mm-thick layers, into 3 elution media. MATERIAL AND METHODS Three bulk-fill (SDR® (SDR), X-tra base (XB) and BEAUTI...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Łagocka R,Mazurek-Mochol M,Jakubowska K,Bendyk-Szeffer M,Chlubek D,Buczkowska-Radlińska J

更新日期：2018-07-07 00:00:00

abstract：:BACKGROUND This study investigated the effect of Astragalus polysaccharides (APS) on radiation-induced bystander effects (RIBE) in human bone mesenchymal stem cells (BMSCs) induced by irradiated A549 cells. MATERIAL AND METHODS A549 cells were irradiated with 2 Gy X-rays to obtain conditioned medium. BMSCs were incuba...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zhang L,Luo Y,Lu Z,He J,Wang L,Zhang L,Zhang Y,Liu Y

更新日期：2018-07-06 00:00:00

abstract：:BACKGROUND Colorectal cancer (CRC) is a common malignant tumor with high incidence and mortality worldwide. The aim of this study was to evaluate the association between differentially expressed genes (DEGs), which may function as biomarkers for CRC prognosis and therapies, and the clinical outcome in patients with CR...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Huang Z,Yang Q,Huang Z

更新日期：2018-07-05 00:00:00

abstract：:BACKGROUND The correlation between serum concentration of neuron specific enolase (NSE), S100B, and the prognosis of patients with acute spinal cord injury (ASCI) remains controversial. MATERIAL AND METHODS Sixty patients with confirmed diagnosis of ASCI were recruited for this study from February 2015 to January 2017...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Du W,Li H,Sun J,Xia Y,Zhu R,Zhang X,Tian R

更新日期：2018-06-30 00:00:00

abstract：:BACKGROUND To investigate the effect of the BMP/Smad signaling pathway on fracture healing and osteogenic ability in senile osteoporotic fracture on humans and rats. MATERIAL AND METHODS Sixty-two patients and well-matched normal controls were enrolled for clinical observation. A rat model of senile osteoporotic fract...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Liu DB,Sui C,Wu TT,Wu LZ,Zhu YY,Ren ZH

更新日期：2018-06-25 00:00:00

abstract：:BACKGROUND The purpose of this study was to evaluate the effects of prosthetic material and framework design on the stress within dental implants and peripheral bone using finite element analysis (FEA). MATERIAL AND METHODS A mandibular implant-supported fixed dental prosthesis with different prosthetic materials [cob...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Arinc H

更新日期：2018-06-22 00:00:00

abstract：:BACKGROUND Lead (Pb) is a widely used metal in modern industry and is regarded as a health hazard. Although lead-induced genotoxicity has been confirmed, the direct evidence that lead induces genotoxicity in human cells and its related mechanisms has not been fully elucidated. In this study, for the first time, we eva...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Liu X,Wu J,Shi W,Shi W,Liu H,Wu X

更新日期：2018-06-22 00:00:00

abstract：:BACKGROUND Improper use of antimicrobials can cause adverse drug events and high costs. The purpose of this study was to investigate the frequency and potential drug-drug interactions associated with antimicrobials among hospitalized patients. MATERIAL AND METHODS This study was conducted on the same day in 5 differen...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Kuscu F,Ulu A,Inal AS,Suntur BM,Aydemir H,Gul S,Ecemis K,Komur S,Kurtaran B,Ozkan Kuscu O,Tasova Y

更新日期：2018-06-20 00:00:00

abstract：:BACKGROUND The purpose of this study was to determine the influence of 2 different esthetic post materials on the final color of direct-composite restorations by using a digital technique under in vivo conditions. MATERIAL AND METHODS We included 22 pulpless incisor teeth treated with conventionally cemented zirconia ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Ayna B,Yılmaz BD,Izol BS,Ayna E,Tacir İH

更新日期：2018-06-15 00:00:00

abstract：:BACKGROUND The aim of this study was to investigate the association between mean platelet volume (MPV), C-reactive protein (CRP), and prognosis in patients with acute ischemic stroke (AIS) following intravenous (IV) thrombolytic treatment. MATERIAL AND METHODS A retrospective clinical study included 129 patients withi...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： İnanç Y,Giray S,İnanç Y

更新日期：2018-06-05 00:00:00

abstract：:BACKGROUND MicroRNA-365 (miR-365) is involved in the development of a variety of cancers. However, it remains largely unknown if and how miRNAs-365 plays a role in melanoma development. MATERIAL AND METHODS In this study, we overexpressed miR-365 in melanoma cell lines A375 and A2058, via transfection of miR-365 mimic...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zhu Y,Wen X,Zhao P

更新日期：2018-06-02 00:00:00

abstract：:BACKGROUND The aim of this study was to investigate the correlation between indocyanine green plasma disappearance rate (ICG-PDR) and allograft function as well as postoperative complications after liver transplantation. MATERIAL AND METHODS In this prospective study, 115 cases of adult liver transplantation performed...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Sun Y,Yu L,Liu Y

更新日期：2018-06-01 00:00:00

abstract：:BACKGROUND Ubiquilin-4 (UBQLN4) is a component of the ubiquitin-proteasome system and regulates the degradation of many proteins implicated in pathological conditions. The aim of this study was to determine the role of UBQLN4 in regulating the proliferation and survival of the normal gastric epithelial cell line GES-1...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Huang S,Dong X,Wang J,Ding J,Li Y,Li D,Lin H,Wang W,Zhao M,Chang Q,Zhou N,Cui W,Huang C

更新日期：2018-05-28 00:00:00

abstract：:BACKGROUND Hepatocellular carcinoma (HCC) is one of the most common malignancies occurring worldwide and is most frequent type of liver cancer. The risk for developing HCC increases with the severity of inflammation and fibrosis. The members of the interleukin-1 (IL-1) family are primarily proinflammatory cytokines du...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Tak KH,Yu GI,Lee MY,Shin DH

更新日期：2018-05-26 00:00:00

abstract：:BACKGROUND Ubiquitin-specific peptidase 33 (USP33) is a deubiquitinase that balances the ubiquitin status of proteins. It has been reported to act as a tumor suppressor in colorectal cancer and lung cancer. However, the expression pattern and clinical significance of USP33 have not been investigated in gastric adenoca...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Chen Y,Pang X,Ji L,Sun Y,Ji Y

更新日期：2018-05-26 00:00:00

abstract：:BACKGROUND In developed countries, prostate cancer (PCa) is a frequently diagnosed cancer with the second highest fatality rate. Circular RNAs (circRNAs) are a class of endogenous non-coding RNAs (ncRNAs) stably expressed in cells and involved in a series of carcinomas. However, few research studies have reported on t...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Dai Y,Li D,Chen X,Tan X,Gu J,Chen M,Zhang X

更新日期：2018-05-25 00:00:00

abstract：:BACKGROUND The aim of this study was to assess the effects of interleukin-1 (IL-1) receptor associated kinase (IRAK) inhibitors on intestinal injury induced by necrotizing enterocolitis (NEC) in neonatal rats and its regulation on the intestinal Toll-like receptor (TLR) inflammatory signaling pathway. MATERIAL AND MET...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Hou Y,Lu X,Zhang Y

更新日期：2018-05-22 00:00:00

abstract：:BACKGROUND Chemotherapy has been assuring more important roles in the treatment of carcinoma. Developing new types of drugs with less adverse effects and low drug resistance has become an important researching focus. The present study aimed to investigate the anticancer effects of 5-hydroxy-4'-nitro-7-propionyloxy-gen...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Bai J,Luo X

更新日期：2018-05-17 00:00:00

abstract：:BACKGROUND The objective of the current study was to guide the early clinical treatment strategies by assessing the recovery of abnormal coagulation in acute promyelocytic leukemia (APL) patients during induction therapy. MATERIAL AND METHODS Retrospective analysis was performed in 112 newly-diagnosed patients with AP...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Song YH,Qiao C,Xiao LC,Zhang R,Lu H-

更新日期：2018-05-17 00:00:00

abstract：:BACKGROUND Microvascular endothelial inflammation and apoptosis are responsible for septic acute lung injury (ALI). Ripasudil is a novel Rho/Rho kinase (ROCK) inhibitor which shows therapeutic effects on several vascular diseases. The aim of this study was to investigate the protective effects and correlated molecular...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Yang J,Ruan F,Zheng Z

更新日期：2018-05-16 00:00:00

abstract：:BACKGROUND The role of multidrug resistance 1 gene (MDR1 or ABCB1) polymorphism G2677T was studied in relation to paroxetine therapeutic efficacy and its side effects, as well as its association with selected demographic and clinical characteristics of patients with depressive disorder. MATERIAL AND METHODS To evaluat...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Vancova Z,Cizmarikova M,Dragasek J,Zofcakova S,Kolarcik P,Mojzis J

更新日期：2018-05-13 00:00:00

abstract：:BACKGROUND The present study aimed to investigate the clinical relevance of fragile histidine triad protein (FHIT) in patients with bladder cancer (BC). MATERIAL AND METHODS Three independent BC microarray studies were collected and reanalyzed. The expression of FHIT was evaluated between BC samples and normal bladder...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Liu XP,Yin XH,Yan XH,Zeng XT,Wang XH

更新日期：2018-05-12 00:00:00

abstract：:BACKGROUND Previous research showed that Jin-Fu-An decoction has a significant effect on lung cancer. However, it remains unclear whether p120ctn and its transcription factor Kaiso play a role in lung cancer cell proliferation, adhesion, migration, and metastasis. MATERIAL AND METHODS Proliferation inhibition was dete...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Sun Z,Cao Y,Hu G,Zhao J,Chen M,Wang S,Ye Z,Chen H,Wang W,Wang Y

更新日期：2018-05-08 00:00:00

abstract：:BACKGROUND This study aimed to investigate intracoronary nicorandil treatment on the no-reflow phenomenon (NRP) during primary percutaneous coronary intervention (PCI) in patients with acute ST-segment elevation myocardial infarction (STEMI) and to compare nicorandil with sodium nitroprusside. MATERIAL AND METHODS Pati...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Qi Q,Niu J,Chen T,Yin H,Wang T,Jiang Z

更新日期：2018-05-04 00:00:00

abstract：:BACKGROUND Although 5-Flourouracil(5-FU) is used as the first-choice treatment for advanced hepatocellular carcinoma (HCC), it is associated with acquired and intrinsic resistance. Hyperactivation of mTOR signaling has been linked to tumorigenesis and chemoresistance in HCC. The aim of this study was to evaluate and c...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zhang Y,Jia QA,Kadel D,Zhang XF,Zhang QB

更新日期：2018-05-03 00:00:00

abstract：:BACKGROUND Sepsis is known to trigger impaired T cell function, which relates to immunosuppression, contributing to refractory infection and high mortality. The mechanisms of T cell recovery remain to be elucidated, and novel and effective therapeutics for sepsis are needed. Ouabain, a small molecule of cardiac glycos...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Niu R,Gao H,Zhou Y,Zhang J

更新日期：2018-05-02 00:00:00

abstract：:BACKGROUND Quercetin is a natural bioactive flavonoid that is present in a wide variety of vegetables and fruits and exhibits a promising anti-metastasis property in various human cancer cells. However, the effect of quercetin on human HCCLM3 cells is unclear. MATERIAL AND METHODS In the current study, a wound-healing...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Lu J,Wang Z,Li S,Xin Q,Yuan M,Li H,Song X,Gao H,Pervaiz N,Sun X,Lv W,Jing T,Zhu Y

更新日期：2018-04-27 00:00:00

abstract：:BACKGROUND Virtual reality (VR) training with motion-controlled console games can be incorporated into stroke rehabilitation programs. The use of a variety of gaming software can provide the patient with an opportunity to perform activities that are exciting, entertaining, and that may not be feasible in clinical envi...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Lee MM,Lee KJ,Song CH

更新日期：2018-04-27 00:00:00

abstract：:BACKGROUND A prospective clinical study was conducted to assess different regimens of steroid therapy and preservation of hearing following cochlear implantation. MATERIAL AND METHODS Study participants were ≥18 years-of-age, with a cochlear duct length ≥27.1 mm measured by computed tomography (CT), with hearing sound...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Skarżyńska MB,Skarżyński PH,Król B,Kozieł M,Osińska K,Gos E,Skarżyński H

更新日期：2018-04-22 00:00:00

abstract：:BACKGROUND Studies on insulin resistance (IR) in chronic kidney disease (CKD) patients are rare, and its exact mechanism remains unclear. In this study, we explored the molecular mechanism of IR with chronic renal failure (CRF) and interventions to alleviate IR in patients with CRF. MATERIAL AND METHODS In vivo and in...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Wang Y,Wei RB,Yang Y,Su TY,Huang MJ,Li P,Chen XM

更新日期：2018-04-21 00:00:00

abstract：:BACKGROUND The impact of hypertensive (HTN) donor grafts on the prognosis of simultaneous liver-kidney transplantation (SLKT) patient is not known, and an applicable risk scoring system for SLKT patient survival is lacking. This study aimed to evaluate the impact of donor HTN on patient survival of SLKT recipients and...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zhu Z,Huang S,Zhao Q,Tang Y,Zhang Z,Wang L,Ju W,Guo Z,He X

更新日期：2018-04-20 00:00:00

abstract：:BACKGROUND Cancer-associated fibroblasts (CAFs) are functionally and structurally essential for tumor progression. There are 3 main origins of CAFs: mesenchymal stem cells (MSCs), epithelial-to-mesenchymal (EMT) transition cells, and tissue-resident cells. Pericytes retain characteristics of progenitor cells and can d...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Ning X,Zhang H,Wang C,Song X

更新日期：2018-04-18 00:00:00

abstract：:BACKGROUND Bladder cancer caused by exposure to aniline dyes, chronic cystitis, and smoking is detected in approximately 70 000 new cases annually. In the USA alone, it leads to 15 000 deaths every year. In the present study, we investigated the role of 3-((4'-amino-[1,1'-biphenyl]-4-yl)amino)-4-bromo-5-oxo-2,5-dihydr...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Guo J,Hu J,Cao R,Chen Q,Li K

更新日期：2018-04-16 00:00:00

abstract：:BACKGROUND The objective of this study was to explore the role of SIX1 in paclitaxel (TAX) resistance of HepG2 cells via reactive oxygen species (ROS) and autophagy pathway. MATERIAL AND METHODS Hepatoma cell line HepG2 was treated with SIX1 knockdown or/and TAX. Cell growth was detected by MTT assay and colony format...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Li B,Zhao S,Geng R,Huo Z,Zhang H

更新日期：2018-04-15 00:00:00

abstract：:BACKGROUND The postoperative adverse cardiovascular events (PACE) after surgery can result in prolonged length of stay and poorer prognosis. The purpose of this Asian single-center study was to investigate the potential predicative role of leptin for PACE in elderly patients undergoing major non-cardiac surgery. MATER...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Gu Z,Sun C,Xiang D

更新日期：2018-04-09 00:00:00

abstract：:BACKGROUND HSP60-related immunological activities are found in normal-pressure glaucoma (NPG) patients, in whom an elevated intraocular pressure (IOP) found in primary open-angle glaucoma (POAG) is not observed. HSP60 was found in POAG and NPG patients, while anti-HSP60 level was mainly found to be higher in NPG patie...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Guo C,Wu N,Niu X,Wu Y,Chen D,Guo W

更新日期：2018-04-04 00:00:00

abstract：:BACKGROUND The aim of this study was to discuss the possible roles and clinical value of 2 circRNAs (hsa_circ_0049224 and has_circ_0049220) in SLE patients. MATERIAL AND METHODS Reverse-transcription real-time polymerase chain reaction (RT-PCR) was conducted to detect the expressions of hsa_circ_0049224, has_circ_0049...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zhang C,Huang J,Chen Y,Shi W

更新日期：2018-04-02 00:00:00

abstract：:BACKGROUND There are few triage methods based on patient age and extent of burn. However, in case of mass casualties, age might be hard to define. Burn segregation in mass-casualty accidents requires an easy, fast, and effective method. Triage in burns should also segregate casualties requiring treatment in burn cente...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Surowiecka-Pastewka A,Witkowski W,Kawecki M

更新日期：2018-03-31 00:00:00

abstract：:BACKGROUND Hypertonic saline (HS) has been successfully used for treatment of various forms of brain edema. Decreased expression of aquaporin (AQP)4 and pro-inflammatory cytokines such as tumor necrosis factor (TNF)-a and interleukin (IL)-1b have been linked to edema pathogenesis. This study examined the effect of 3% ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Yin J,Zhang H,Chen H,Lv Q,Jin X

更新日期：2018-03-30 00:00:00